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Our Mission

The mission of PREP - a Threshold Foundation Funding Circle - is to support research, organizations, and initiatives that facilitate the safe, thoughtful, and legal use of psychedelics as tools for medicinal and spiritual benefit.

Our Strategy and Focus

Over the past few years the world has seen unprecedented momentum in the research and study of psychedelics. From studies on working with addiction and treatment resistant PTSD to matters of criminal justice, there is renewed interest in understanding the medicinal and spiritual benefits of these medicines. In an extraordinary New Yorker piece, Michael Pollan wrote that “the revival of psychedelic research today owes much to the respectability of its new advocates.”

In a manner similar to lifting a boat, we seek to support a variety of facets of this movement at once— building community, enabling research, promoting education, and campaigning for sensible drug policy reform.

2019 Grant Recipients

California Institute of Integral Studies

Drug Policy Alliance

Hefftner Research Institute

International Center for Ethnobotanical Education, Research, and Service

Ketamine Research Foundation

Mission Within

Students for a Sensible Drug Policy

Grant Cycle Guidelines:


We provide program support as well as general operating support, and usually do not fund organizations with budgets larger than $2 million.


We fund organizations with 501(c)3 and 501(c)4 statuses.


We fund organizations that work both within the U.S. and internationally.